Pharmacology Models

Complete listing of pharmacology models, including specific models and species is available on The Concourse, or contact Deborah Curry at dcurry@biomere.com

Metabolic Disease Models

Indications

  • Obesity
  • Type 1 diabetes mellitus
  • Type 2 diabetes mellitus
  • Hyperlipidemia/Hypercholesterolemia
  • Atherosclerosis
  • Hyperuricemia

Diabetes Complications

Indications

  • Diabetic nephropathy
  • Delayed diabetic wound healing
  • Diabetic neuralgia

DIGESTIVE DISORDERS

DIGESTIVE DISORDERS

Indications

  • Acute gastric ulcer
  • Chronic gastric ulcer
  • Acute and chronic liver injury/fibrosis
  • Hepatic fibrosis/decompensated cirrhosis
  • Nonalcoholic fatty liver disease (NASH)

CNS – CENTRAL & PERIPHERAL NERVOUS SYSTEM DISEASES

Nerves

Indications

  • Alzheimer’s disease
  • Parkinson’s disease
  • Depression/Anxiety
  • Epilepsy
  • Sleep/Sedation/Anesthesia Induction
  • Pain
  • Stroke
  • Spinal Cord Injury (SCI)
  • Drug dependence
  • Migraine
  • Somatic neurotoxicity

INFLAMMATION & AUTOIMMUNE DISEASE

Indications

  • Rheumatoid arthritis
  • Systemic lupus erythematosus (SLE) model
  • GvHD
  • Ulcerative colitis
  • EAE
  • Psoriasis
  • Atopic dermatitis models
    Sepsis

Blood Disorders

Indications

  • Coagulation disorders
  • Granulocyte/thrombocytopenia
  • Anemia

INFECTIOUS DISEASE

infectious disease

Indications

  • Influenza
  • HBV infection

ENDOCRINE DISEASE

Indications

  • Osteoporosis

REPRODUCTIVE SYSTEM DISEASE

Indications

  • Asthenospermia
  • Primary ovarian insufficiency

UROLOGIC DISEASES

Indications

  • Acute kidney injury
  • Chronic kidney disease/renal fibrosis

DERMAL

Indications

  • Wound healing
  • Burn

Complete listing of pharmacology models, including specific models and species is available on The Concourse, or contact Deborah Curry at dcurry@biomere.com

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