PK/PD Studies That De-Risk Your Path to IND

Expert pharmacokinetics, pharmacodynamics, bioanalysis, and translational support for preclinical drug development.

Biomere supports preclinical drug developers by generating PK/PD data needed to guide dosing levels and routes, evaluate exposure-response, support early toxicology decisions, and move confidently toward IND-enabling studies.

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Get Reliable PK/PD Data Without Black Box Friction or Waiting in Line

When every study decision matters, you need more than data. You need a responsive scientific partner who can help design the right study, execute efficiently, and interpret results in the context of your development goals. Biomere’s scientists work closely with clients and frequently host clients on-site to observe and participate in procedures. Our transparent approach ensures clients know study status in real time and are aware of challenges and mitigations immediately.

How Biomere Can Support

  • PK/PD study design and execution in rodent, primates and rabbit models. 
  • Pharmacokinetics and pharmacodynamics (PK/PD) studies in both in vivo and in vitro models. 
  • Dose-response analysis
  • Drug metabolism and biodistribution studies
  • Bioanalysis and biomarker evaluation
  • Early toxicology insights

Built for High-Value Preclinical Decisions

Optimize dosing strategy

Generate exposure, response, and biomarker data to inform dose selection and development planning.

De-risk before GLP toxicology

Use early PK/PD and toxicology insights to identify risks before committing to larger IND-enabling programs.

Work directly with experienced scientists

Collaborate with a high-touch CRO team that understands complex preclinical development requirements.

Integrate in vivo studies with downstream analysis

Simplify complex programs with coordinated study execution, sample handling, bioanalysis, and interpretation.

PK/PD Support Across Modalities & Stages

Biomere provides flexible PK/PD support across drug modalities and development stages to translate preclinical findings into actionable insights for efficacy and safety study planning.

Pharmacokinetics

Understand absorption, biodistribution, metabolism, exposure, clearance, and bioavailability.

Pharmacodynamics

Measure biological response, target engagement, biomarkers, and dose-response relationships.

Bioanalytical Support

Support drug quantification, biomarker analysis, LC-MS/MS workflows, and assay-driven insights.

Early Toxicology Support

Generate early toxicology data across small molecules, biologics, cell therapies, and gene therapy programs.

Why Biomere for Your Study?

  • Quick study start times once animals are available. 
  • Flexible study design
  • High-touch scientific collaboration with the option for on-site visits and participation
  • Experience with various modalities including small molecules, biologics, oligos, viral vectors, LNPs and complex nanoparticles, cell and gene therapies.
  • Integrated in-life and sample analysis to generate actionable data. 
  • Responsive alternative to large CRO providers
  • Strong fit for pharma companies, large and mid-size biotechs as well as startups.

Designed for Biotech and Pharma Teams That Need Answers Quickly

Whether you are preparing for IND-enabling studies, evaluating a new modality, comparing dose levels, or looking for a more responsive CRO partner, Biomere can help you generate decision-ready data.

Ready to Plan Your PK/PD Study?

Talk with Biomere’s scientific team about your program goals, timelines, model requirements, dosing strategy, and study design needs.

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