joinn
laboratories

JOINN LABORATORIES CHINA:

(Suzhou, Beijing, Wuzhou, Chongqing, and Guangzhou)

JOINN Laboratories is the largest public nonclinical CRO in China with facilities in non-clinical and clinical facilities in Beijing, Suzhou and Chongqing, and a non-clinical facility in Guangzhou. Additionally, there are 3 dedicated Lab Animal and Models sites in Wuzhou, Yunnan and Nanning. JOINN Laboratories has successfully completed multiple accreditations and certification including AAALAC accreditation and US FDA GLP inspection. The company expanded into the US with sites in Richmond CA and Worcester MA to serve the major biotech hubs. U.S. East and West Coasts in major biotech hubs.

JOINN Laboratories has grown to over 2,500 employees worldwide and the core team includes experienced executives who have an average of 25 year experience in the drug development and regulatory review areas.

Joinn Laboratories Services

JOINN Laboratories has successfully completed several toxicology programs for different biologics including bi-specific antibodies, antibody-drug conjugates (ADCs), fusion proteins, peptides, vaccines and cell and gene therapies.

2,500 employees | Over 500 projects completed per year | over 5000 GLP toxicology programs completed

JOINN Laboratories has partnered with multiple US and EU based biotech and pharmaceutical companies at its multiple facilities that meet international standards (GMP, GLP and GCP). The facilities use multiple small and large animal models including rats, mice, hamsters and ferrets as well as primates and swine. JOINN clients have the benefits of a wide range of disease and pharmacology animal models, expedited study start times and budget-friendly pricing.

services

JOINN Laboratories offers a comprehensive portfolio of end-to-end preclinical drug discovery and development services.

services

  • In vitro and in vivo efficacy and pharmacology studies
  • Early PK/PD studies and evaluation of ADME characteristics
  • Early toxicity screening
  • Antibody discovery using phage display or hybridoma
  • Antibody screening and optimization
  • Monoclonal antibodies, recombinant protein production and purification

DMPK and Bioanalysis Services

  • PK/PD studies in small and large animal models
  • DMPK method development and GLP method validation
  • Biomarker discovery and method validation
  • In vitro and in vivo ADME studies

Safety Assessment Services

  • Comprehensive IND-enabling safety assessment programs
  • Developmental and Reproductive Toxicology (DART)
  • Genetic Toxicology
  • Carcinogenicity Studies Juvenile Animal Study (JAS)
  • Immunogenicity and Immunotoxicity
  • Drug Abuse & Substance Dependence
  • Custom and specialized toxicity studies available

Clinical Services

  • Clinical Bioanalysis including PK/PD method validation, ADA method development and validation, RO and immunotyping, immunogenicity and potency of vaccines.
  • Phase I clinical research units that offer:
    • Screening and evaluation of trial centers
    • Provision of Co-PI service
    • Third-party audits
    • GCP consultation services
  • Pharmacovigilance
    • PV System Set Up with Continuous Improvement
    • ICSR and Signal Management
    • Benefit-Risk Management
    • Aggregate Safety Reports
    • Literatures Services
  • Other Services:
    • Regulatory Affairs Advisory services
    • Clinical Operations
    • Quality Management
    • Data Management, Statistical Analysis and Reporting

cdmo services

  • Cell Line Development including CHO-K1 cell banks including glutamine synthase (GS) knockdown cell lines and Fucose knock-down cell banks
  • Culture Media Formulation
  • Mammalian and microbial fermentation systems that ranges from 50 liters to 2,000 liters
    • Scale up to over 100,000 liters available
  • Analytical Development
    • Batch release testing
    • Test method development and verification
    • Stability studies
    • Protein Characterization
    • Original and auxiliary package testing

Our global liaison team paves the way to extended resources, abundant pharmacology models and budget friendly options seamlessly.