CRO Expertise

PK/PD Efficacy Models

We perform a wide range of non-clinical laboratory studies that support new drug applications (NDAs) for permits regulated by the Food and Drug Administration (FDA). We offer rapid, quality-controlled pharmacokinetic (PK) studies to test the bodily absorption, distribution, metabolism, and excretion of your compound. Biomere can evaluate the effectiveness of your compound using our proprietary research models or other commercially available models.

Biomere specializes in providing preclinical consulting services and early-stage drug discovery and development services in rodent species.

Our customized experiments are personalized to your needs and always include:

• Qualified, experienced scientists and technical staff
• Protocol development
• Twenty-four hour, on call veterinarian service
• Non-GLP studies
• Use of several animal models including: mouse, rat, guinea pig,
  hamster, rabbit, marmoset and macaque
• All routine methods of administration

Articles

A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor

RUC-4 A Novel αIIbβ3 Antagonist for Pre-hospital Therapy of Myocardial Infarction

Posters

A Dose Range Finding and Pharmacokinetics Study of RUC-4 Succinate Alone and In Combination with Aspirin in Nonhuman Primates

Dose Range-Finding Toxicity Study of RUC-4 Administered by Subcutaneous Injection in Mice

Comparison/Techniques/Macaca Fasciciularis Peripheral Blood Mononuclear Cells