PK-PD

CRO Expertise


BIOMERE PK/PD EFFICACY SUPPORT

Biomere offers rapid, quality-controlled pharmacokinetic (PK) and pharmacodynamic (PD) studies to test your novel compound for distribution. Models Include: mice, rats, guinea pigs, hamsters, rabbits, and macaques.

Our NHP program includes a large colony of naïve and non-naïve cynomolgus and rhesus macaques supporting PK/PD discovery research. We utilize a variety of different compound administration and sample collection techniques. Biomere is proficient in conducting xenograft studies, as well as large and varied tissue biopsy and intrathecal programs.

Examples of comparative PK NHP data below:


NHP OVERVIEW

COMPLIANCE & ACCREDITATION

Articles

A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor

RUC-4 A Novel αIIbβ3 Antagonist for Pre-hospital Therapy of Myocardial Infarction

Posters

A Dose Range Finding and Pharmacokinetics Study of RUC-4 Succinate Alone and In Combination with Aspirin in Nonhuman Primates

Dose Range-Finding Toxicity Study of RUC-4 Administered by Subcutaneous Injection in Mice

Comparison/Techniques/Macaca Fasciciularis Peripheral Blood Mononuclear Cells

JOINN Locations

Joinn Locations